Agenda is subjected to changes

Time Day 1, 3 November 2022
8.00 Registration
8.50 Opening Address
9.00 Keynote

Psychosis: Progress in understanding complex brain disease
Steven E. Hyman, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, Harvard University Distinguished Service Professor, USA
10.00 Break
10.30 Plenary
The design of clinical data collection in molecular genetic studies of psychiatric illness
Kenneth Kendler, Virginia Commonwealth University, USA
11.15 Clinical Neurosciences
Transdiagnostic network analysis of negative symptoms (Virtual)
Raymond Chan, Chinese Academy of Sciences, China
Chairperson: Dr Jimmy Lee, Institute of Mental Health
12.00 Lunch
13.30 Plenary
Clinical-course Phenotypes in Schizophrenia Spectrum Disorders
Eric Chen, University of Hong Kong, Hong Kong, China
14.15 Clinical Neurosciences
Brain network breakdown in neuropsychiatric disorders and at-risk individuals
Helen Zhou, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Chairperson: Dr Jimmy Lee, Institute of Mental Health
14.45 Clinical Neurosciences
Discovering the biology of major psychiatric disorders in India
Biju Viswanath, National Institute of Mental Health and Neurosciences, India
15.15 Break
15.45 Education
Scalable analysis of DNA sequence data and its applications in brain-disorder studies
Anne Feng, National Taiwan University & Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA
16.15 Education
Transplanting Emotional Variance Analysis from learning to mental health prediction
Wilson Goh, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
17.00 End
Time Day 2, 4 November 2022
8.00 Education
Genetics of Human Complex Disorders
Hailiang Huang, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA
8.30 Education
Leveraging human pluripotent stem cell models to study neuropsychiatric disorders
Ralda Nehme, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA
Olli Pietiläinen, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA & University of Helsinki, Finland
Chairperson: Hailiang Huang, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard
9.00 Plenary
Genetic Studies of Brian Disorders: Singapore Perspective
Jianjun Liu, Genome Institute of Singapore, A*STAR, Singapore
10.00 Break
10.30 Genetics
Cognition as a window into psychopathology and beyond
Max Lam, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA & Institute of Mental Health, Singapore
Chairperson: Hailiang Huang, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard
11.00 Genetics
Strategies for large scale genome health collections, examples from Finland
Aarno Palotie, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA & University of Helsinki, Finland
11.30 Genetics
Functional Interpretation of GWAS
Chunyu Liu, SUNY Upstate Medical University, USA
12.00 Lunch and Poster Session
13.30 Plenary
Disease mechanisms and therapeutic strategies for SNAREopathies, syndromes caused by mutations in presynaptic genes
Matthijs Verhage, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam and Amsterdam University Medical Center, Netherlands
14.15 Translational Neurosciences
FEZ1 deletion contributes to human brain development disorders
John Chua, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Chairperson: Jai Polepalli, Yong Loo Lin School of Medicine, National University of Singapore
14.45 Translational Neurosciences
A synapsin SNP associated with schizophrenia impairs synaptic function (Virtual)
George Augustine, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
15.15 Break
15.45 Translational Neurosciences
Evaluating the use of neurosteroids as potential treatments for schizophrenia in mouse models
Peiyan Wong, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Chairperson: Jai Polepalli, Yong Loo Lin School of Medicine, National University of Singapore
16.15 Translational Neurosciences
Sleep EEG signatures of Schizophrenia patients – the GRINS study
Jen Pan, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA
17.00 End
Time Day 3, 5 November 2022
8.00 Plenary
Human brain organoids and the quest to understand neuropsychiatric disease (Virtual)

Paola Arlotta, Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard, USA & Harvard University, USA
9.00 Plenary
Pathways forward from psychiatric genetics
Naomi Wray, University of Queensland, Australia
10.00 Break
10.30 Genetics
Genomic insights into disease-associated non-coding variants
Yin Shen, Institute for Human Genetics, University of California, San Francisco, USA
Chairperson: Max Lam, Institute of Mental Health
11.15 Genetics
Genetics of major depressive disorder: dissecting mechanism from 500 SNP associations
Cathryn Lewis, King's College London, UK
12.00 Farewell

Confirmed Speakers

Steven E Hyman

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA

Harvard University, USA

Kenneth Kendler

Virginia Commonwealth University, USA 

Raymond Chan

China Academy of Sciences, China

Eric Chen

University of Hong Kong, Hong Kong, China

Helen Zhou

Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Biju Viswanath

National Institute of Mental Health and Neurosciences, India

Anne Feng

National Taiwan University

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA

Wilson Goh

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

Hailiang Huang

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA

Ralda Nehme

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA

Olli Pietiläinen 

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA 

University of Helsinki, Finland

Jianjun Liu 

Genome Institute of Singapore, A*STAR, Singapore

Max Lam

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA  

Institute of Mental Health, Singapore

Aarno Palotie

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA 

University of Helsinki, Finland

Chunyu Liu

SUNY Upstate Medical University, USA

Matthijs Verhage

Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam and Amsterdam University Medical Center, Netherlands

John Chua

Yong Loo Lin School of Medicine, National University of Singapore, Singapore

George Augustine

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

Peiyan Wong

Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Jen Pan

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA

Paola Arlotta

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, USA 

Harvard University, USA

Naomi Wray

University of Queensland, Australia

Yin Shen

Institute for Human Genetics, University of California, San Francisco, USA

Cathryn Lewis

King's College London, UK